About Us

Trichloroisocyanuric acid (TCCA) and other reagents

Trichloroisocyanuric acid (TCCA) and N-chlorosuccinimide (NCS) were found to be mild and efficient reagents for the direct oxidative conversion of sulfur compounds to the corresponding arenesulfonyl chlorides in good-to-excellent yields through the oxidative chlorination. The overall process is simple and practical, and it provides convenient access to a variety of aryl or heteroarylsulfonyl chlorides. The mild reaction conditions and the broad substrate scope render this method attractive and complementary to existing syntheses of aryl or heteroarylsulfonyl chlorides.
Trichloroisocyanuric acid (TCCA) was found to be a highly efficient homogeneous catalyst for synthesis of imidazoles via one-pot, three-component condensation of aldehydes with benzil and ammonium acetate. The valuable advantages of this method are high yields of products, easy work-up and purification procedure, and use of a commercially available, inexpensive, and non-volatile catalyst.
A typical test fishery drugs Trichloroisocyanuric acid (TCCA), ciprofloxacin (Ciprofloxacin hydrochloride, CPFX) Chlorella pyrenoidosa (Chlorella pyrenoidosa) acute toxicity and phase Ⅰ, Ⅱ phase metabolic enzymes activity. the results showed that, TCCA and CPFX role chlorella after 96h EC50 were 0.31mg · L ^ -1 and 20.61mg · L ^ -1.TCCA at low concentrations of Chlorella ⅰ, ⅱ phase metabolic enzymes GSH, GST, CAT and EROD induction exist, when ^ -1 TCCA concentrations greater than 0.13mg · L, induction of GSH, GST and EROD weakened response .GSH, GST, EROD three enzymes CPFX weak action when CPFX more than 70.20mg · L ^ -1, GST was significantly inhibited, whereas EROD was significantly increased compared with the control group, the difference was significant, GSH did not change significantly .CAT more sensitive response to CPFX effect, the performance of a typical adaptive induced phenomenon "bell curve", suitable for biomarkers of CPFX.