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Trichloroisocyanuric Acid(TCCA): A Safe and Efficient Oxidant

The literature on trichloroisocyanuric acid (TCCA) has been reviewed. TCCA is a safe and efficient reagent, useful for chlorination and oxidation even on large scale. Another article is: Efficient Tetrahydropyranylation of Alcohols and Detetrahydropyranylation Reactions in the Presence of Catalytic Amount of Trichloroisocyanuric Acid (TCCA) as a Safe, Cheap Industrial Chemical. Preparation and cleavage of THP ethers of different hydroxy functional groups are easily and efficiently performed in the presence of trichloroisocyanuric acid (TCCA) in the absence of solvent with high yields.
An efficient three-component synthesis of 3,4-dihydropyrimidinones using trichloroisocyanuric acid (TCCA) as a mild, homogeneous and neutral catalyst for Biginelli reaction in ethanol or DMF under reflux condition and microwave irradiation is described. Yields are excellent in either of the two conditions. Methods: use physical and chemical properties of the detection method, suspension quantitative germicidal test, field disinfection test.The homemade trichloroisocyanuric acid (TCCA) effervescent difference in weight, the disintegration time of detection are in line with the "Chinese Pharmacopoeia" requirement, the mass fraction of chlorine content is 48.71%, 54 ℃ constant temperature storage of 14 d, the average decline rate of chlorine content is 2.88%.