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trichloroisocyanuric acid (TCCA) was used as halogenation reagent

According to party secretary of Nanjing Sports School Indentification introduction, Wang is in the swimming pool with the water quality monitors support staff, has been working for 11 years, after the swimming pool disinfection Swimming pool open end of the day have to do the work, but swimmers Not all cases of departure, Wang advance this work, accidentally spilled trichloroisocyanuric Acid (TCCA) and handling errors, leading to the incident. Nanjing Sports School held a meeting this morning, for Wang made the dismissal decision and to pursue other responsibilities under the circumstances, at the same time, ordered the curator swimming pool suspended inspection. And also the evening of 9 Nanjing Sports Bureau investigation team set up a time, this incident conducted a preliminary investigation, found the incident for staff operating in violation of the provisions lead to Wang, is one accident should not have happened. Responsibility for dealing with the event will be a joint investigation departments to make.
The halohydrination of a double bond has been widely reported using N-halogen species such as trichloroisocyanuric acid (TCCA), tribromoisocyanuric acid (TBCA), N-bromosuccinimide (NBS) and N-chlorosuccinimide (NCS). Our research focused on searching for an effective N-halogen reagent for the halohydrination of the ester. Various N-halogen species, including NCS, TCCA, 1,3-dichloro-5,5-dimethylhydantoin (DCDMH), NBS, TBCA and 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) were evaluated for this halohydrin reaction in acetone : H2O (10:1). It was observed that the reaction proceeded well only when TBCA was used as the halogenation reagent and when performed at a relatively high temperature.
Compared with TBCA, when trichloroisocyanuric acid (TCCA) was used as halogenation reagent, we found that the desired product was accompanied by the formation of a side product in the ratio of 7:3, and the structure of 12 was confirmed by LiAlH4 reduction (in reflux THF for 2 h) affording 2β-hydroxyprovitamin D3.